Interested candidates should submit their cover letter, CV, and 3 references (contact information only) to Travis Barnard at travis.barnard@ucsf.edu.

Senior Research Scientist (Molecular and Cell Biology)

We are seeking to recruit an outstanding candidate to fill a Senior Research Scientist position. The ideal candidate will be able to independently develop, guide, and complete research projects and train lab personnel.

Job responsibilities include but are not limited to:

  • Working independently and collaboratively to develop and complete research projects
  • Training lab members, including guiding and troubleshooting experiments for PhD students, postdocs, and laboratory staff
  • Assisting with the development of grant proposals.

Required qualifications:

  • Possess a PhD degree or equivalent research experience.
  • Applicants need to be self-motivated, fast learners, critical thinkers, and enthusiastic about science and medicine.
  • Demonstrated ability to work as part of a team and independently.
  • Strong ability to problem solve and troubleshoot experiments.
  • At least 2 years of experience working with mammalian cell lines in culture.
  • Experience performing basic molecular biology techniques, including molecular cloning, nucleic acid isolation, PCR, and protein expression analysis.

Preferred qualifications:

  • Postdoctoral training with expertise in cancer biology.
  • Experience culturing primary human organoids.
  • Experience performing gene transfer studies using lentiviral infection of human cell cultures.
  • Experience performing knock-down experiments using shRNA lentiviral infection and CRISPR-based techniques.
  • Experience managing mouse colonies and conducting xenograft studies in mice.

Research Specialist

    We are seeking to recruit an outstanding candidate to fill a Specialist position at the Junior, Assistant, or Associate Level.

    The role of the Specialist is to both assist with ongoing experiments and, depending on the candidate’s skill level, conduct independent research under the guidance of Dr. Feng and other members of the Feng Lab. The Specialist will learn and utilize a variety of research techniques and have the opportunity to be a co-author on publications.

    Job responsibilities include but are not limited to:

    • Applying a range of molecular biology techniques, including molecular cloning, DNA and RNA isolation, and protein expression analysis.
    • Performing flow cytometry and immunohistochemistry.
    • Performing knock-down experiments using shRNA lentiviral infection and CRISPR-based techniques.
    • Performing gene transfer studies using lentiviral infection of human cell cultures.
    • Culturing primary human organoids and established human cancer cell lines.
    • Assisting with mouse colony management, including setting up breeding, weaning, tagging and PCR genotyping.
    • Conducting xenograft studies and pharmacologic experiments in mice.
    • Assisting with lab maintenance duties.

    Required qualifications:

    • Applicants need to be self-motivated, fast learners, critical thinkers, and enthusiastic about science and medicine.
    • Applicants need to work well as part of a team and have outstanding written and oral communication skills.
    • Specialists appointed at the Junior rank must possess a baccalaureate degree (or equivalent degree).
    • Specialists appointed at the Assistant or Associate rank must possess a master’s degree (or equivalent degree) or a baccalaureate degree plus two years of research experience.

    Preferred qualifications

    • Prior independent research experience in molecular and cellular biology or tumor immunology.
    • Experience with flow cytometry, mass cytometry (CyTOF), and/or immunohistochemistry.
    • Experience with molecular biology and biochemistry techniques, cell culture, CRISPR/Cas9, qPCR, confocal microscopy, and/or managing a mouse colony.
    • Preference for the Junior Specialist position may be given to applicants interested in pursuing a biomedical sciences PhD or MD/PhD.

    Postdoctoral Fellows

    Highly motivated individuals with strong backgrounds in molecular biology are being recruited. Potential projects include the identification and characterization of genes involved in prostate cancer pathogenesis, the development of targeting strategies for novel kinases implicated in prostate cancer progression, and the investigation of novel therapeutic combinations. Techniques range from CRISPR and small molecule screening to standard molecular and cell biology approaches to in vivo mouse modeling

     

    Interested candidates should submit their cover letter, CV, and 3 references (contact information only) to Travis Barnard at travis.barnard@ucsf.edu.